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Hypothyroidism: The Unsuspected Illness
 

Eric Bakker ND

Your thyroid is a butterfly-shaped bi-lobed gland located at the base of your neck, just below your Adam's apple. Every single aspect of your metabolism, from the rate at which your heart beats to how quickly you burn calories, are precisely regulated by thyroid hormones.

As long as your thyroid releases the right amounts of these hormones at the right time, your system functions normally and like clockwork. But sometimes your thyroid doesn't produce enough hormones, or produces far too much of one hormone, upsetting this precision and resulting in an imbalance in your body. This condition is known as hypothyroidism.

Hypothyroidism is a common, very treatable disorder that currently is very poorly managed by medicine with the current drug-based approach. And how many people do you know who show many of the signs and symptoms of hypothyroidism, yet come back completely normal on the blood-tests?
A most informative seminar was recently held in Auckland at the Heritage Hotel, last Saturday 29 March by Dr John Lee who specialises in thyroid conditions. He helps patients in his clinic with hormonal imbalances with natural hormone therapies.
The seminar was well attended with a mixture of general medical practitioners as well as natural medicine practitioners.

Hypothyroid prevalence 1.

Many people, mainly women older than age 40, have an under-active thyroid. Men can also get hypothyroidism. Because hypothyroidism usually develops slowly, only about half of all cases are diagnosed early.

  • NZ's prevalence is partly due to low selenium levels in the soil.

  • About 15% of women aged 35 to 60 are affected to some degree by hypothyroidism.

  • 15% - 20% of women over the age of 60 are affected by sub-clinical hypothyroidism.

  • 50% of people who have it are unaware that they have hypothyroidism.


  • Most sub-clinical cases of hypothyroidism go undiagnosed. When blood levels of thyroid hormones are found to be normal, the patient is deemed to be "euthyroid", or having a normal functioning thyroid (inspite of having signs & symptoms).
    Hypothyroidism is believed to be more prevalent than once thought, with up to 1 in 10 of the population is believed to be affected by some degree of hypothyroidism.

    Are you hypothyroid?
    At first, you may have few noticeable symptoms, or you may just feel tired and sluggish. The signs and symptoms of hypothyroidism vary widely, depending on the severity of the hormone deficiency. Be careful before self-diagnosing: The below mentioned signs and symptoms can also be attributed to many other illnesses. Many people falsely attributing their weight gain to an underactive thyroid, when in fact it may be simply that they never exercise!
  • Fatigue: the most common
  • Voice hoarse
  • Eyes can be gritty, burning, itchy, blurry, puffy eyelids.
  • Skin can become dry, cold, rough and scaly.
  • Sex drive: none or poor.
  • Cholesterol elevated: unexplained high or resistant levels.
  • Skin itchy in various places, itchy patches.
  • Hair becomes coarse, brittle and grows slowly or may fall out excessively.
  • Eyebrows thinning, losing outer 1/3 of eyebrow.
  • Sensitivity to cold, feelings of being chilly in rooms of normal temperature.
  • Difficult for a person to sweat, their perspiration may be decreased or even absent even during heavy exercise and hot weather.
  • Constipation that is resistant to magnesium supplementation and other mild laxatives is also another common symptom.
  • Difficulty in losing weight despite rigid adherence to a strict diet seems to be a common finding especially in women.


  • TSH: the big myth
    An interesting point which Dr Lee made was the inaccuracy of the current way of blood- testing patients to determine whether somebody is hypothyroid. So, when a doctor checks your blood for three thyroid hormone markers, they are basing this generally on the reading of the hormone called TSH (thyroid stimulating level). These tests should be abandoned because they are unreliable as gauges of thyroid function. We should be favouring the temperature test instead, according to Dr. Lee.

    The most common traditional way to diagnose hypothyroidism is with a TSH that is elevated beyond the normal reference range. The big myth that persists regarding thyroid diagnosis is that an elevated TSH level is required before a diagnosis of hypothyroidism can be made. There is no question that this will diagnose hypothyroidism, but it is far too insensitive a measure, and the vast majority of patients who have hypothyroidism, particularly those patients who are classified as sub-clinical, will be missed.
    Clinical studies2 have demonstrated that treatment of hypothyroidism with combination thyroid hormone (T4, T3) therapy is more effective than treatment with Thyroxine (T4) alone.

    What you can do
    There is one simple thing almost anyone can do at home to uncover an under- functional thyroid: take your own temperature. The "basal body temperature" test was developed by Dr Broda Barnes, PhD, a physician who, for decades, helped raise the consciousness of both doctors and their patients regarding the risks and prevalence of hypothyroidism and weak thyroid function. His book 3 still remains as the best clinical description of the syndrome.

    Because thyroid hormone is so vital to cellular metabolism, reduced thyroid function manifests as a drop in body temperature to below the normal level of 36.7 C (98.6F).

  • Use a digital thermometer, they are the easiest & most accurate ones to use.


  • Leave it there for 5 minutes (or until it beeps!) and record the temperature for a whole month.     Do this before you get out of bed (the normal temperature on rising will be between 36.4 Centigrade to 36.9 Centigrade. (97.8 - 98.2 Fahrenheit). Check and record the temp also a couple of times at regular intervals throughout the day.


  • I'd recommend an Excel spreadsheet (computer), otherwise draw up a chart with the columns date, morning temp, These recorded levels will help establish your temperature trend, which becomes easy to plot over a month.


  • If your temperature is 36.1 Centigrade or less for 3 to 5 consecutive days, one could conclude that the thyroid function is fairly compromised. You may have hypothyroidism. However, it could also indicate adrenal fatigue or exhaustion. Head for your Naturopath or nutritionally oriented GP.


  • Even if you have had a blood test and were told you did not have a low thyroid reading, you might go back and look at the results again. You may find that your blood levels of thyroid hormones are actually low normal. Many people who are within the so-called "normal" range but below the midpoint could benefit tremendously from thyroid treatment.


  • If you miss a reading or a day, that is ok, but try to be consistent.


  • Hair analysis
    I would also recommend doing a hair analysis if you suspect hypothyroidism. It is an excellent way to determine your level of iodine, selenium, zinc, which are critical in thyroid hormone metabolism. Hair is also a good screening tool for the presence of heavy metals such as lead, mercury, arsenic or cadmium, all which may bind with selenium, reducing the amount available to convert T4 (the inactive hormone) to T3 (the active form), remembering that selenium is already in short supply due to deficiencies in the average NZ diet. Many people present to their doctors and naturopaths with frank mineral deficiencies, a simple test such as a hair analysis can help pinpoint the problem. Check with your health-care practitioner about hair-analysis.

    Natural Thyroid Management
    Iodine: It is estimated the thyroid gland must capture approximately 60 mcg iodide daily to ensure an adequate supply for thyroid hormone synthesis. Ensure you eat sea minerals or have seafood in your diet. Kelp is a good source of iodine. If you take a look at the MOH (NZ Ministry of Health) website you will even find references to the government's concerns that our children are not getting sufficient iodine in their daily NZ diet. The answer? Supplement. Give your children a good children's multi vitamin & mineral daily. Ensure they have sufficient iodine in their diet, give them sea salt (with iodine) and not 'table salt' which has been iodine enriched.

    Although doctors generally recommend synthetic thyroxine (T4) for hypothyroid, it is important to remember that you do have options, you can take charge of your health and what you take, and do not necessarily have to stay on prescribed thyroxine for life. Natural treatment options are now available for the natural hormone management of thyroid conditions.

    This is one condition I would not give advice regarding what to take, without consulting with the patient on an individual basis. I would never recommend self-medication when it comes to the thyroid, it is always best to consult your health-care professional. You nutritionally-oriented Doctor or Naturopath can best help you with your natural treatment of hypothyroidism.

    References:

    1. The many benefits of natural thyroid. Life Enhancement. February 2001.
    2. Bunevicius, R., et al. Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism. New England Journal of Medicine. 340(6):424-429, 1999.
    3. "Hypothyroidism: The Unsuspected Illness", 1976, Dr Broda Barnes, PhD.

    Selenium deficiency causes thyroiditis
    In areas with severe selenium deficiency there is a higher incidence of thyroiditis due to a decreased activity of selenium-dependent glutathione peroxidase activity within thyroid cells. Selenium-dependent enzymes also have several modifying effects on the immune system. Therefore, even mild selenium deficiency may contribute to the development and maintenance of autoimmune thyroid diseases. Selenium substitution may improve the inflammatory activity in patients with autoimmune thyroiditis, especially in those with high activity. Whether this effect is specific for autoimmune thyroiditis or may also be effective in other endocrine autoimmune diseases has yet to be investigated.

    Gartner, R., et al. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations. Journal of Clinical Endocrinology & Metabolism. 87(4):1687-1688, 2002.

    Hypothyroidism improves with selenium
    In a randomised, prospective, blinded study in patients with autoimmune thyroiditis, selenium supplementation of 200 µg/day for three months decreased thyroid (peroxidase) specific antibodies from 100 percent to 63.6 percent. Even more importantly, nine of 36 patients had complete normalisation. TPOAb levels are thought to be specific for autoimmune thyroiditis, as they reflect thyroid inflammation.

    Gartner R, Gasnier BC, Dietrich JW, et al. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    J Clin Endocrinol Metab 2002; 87:1690-1691.

    High intakes of selenium might be detrimental
    Available animal and human evidence strongly supports a relationship between altered thyroid hormone metabolism and selenium deficiency, although evidence also suggests high intakes of selenium might exert a detrimental influence on thyroid hormone metabolism. In animals fed a diet supplemented with high amounts of selenium, serum T3 concentrations are actually reduced by 50 percent, while T4 and fT4 remain unaffected when compared to animals fed a selenium-adequate diet.114

    Eder K, Kralik A, Kirchgessner M. Effect on metabolism of thyroid hormones in deficient to subtoxic selenium supply levels. Z Ernahrungswiss 1995;34:277-283. [Article in German]



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